Module 2 The Endocrine System

1.2.2 page 7

Reflect and Connect

So, who is in charge of the endocrine system? Is it the hypothalamus, the pituitary gland or both? To review the connections between the hypothalamus and the pituitary gland watch the following video

Relationship between the Hypothalamus and the Pituitary Gland

 

Then, using what you have learned in this lesson about the hypothalamus, the posterior, and the anterior pituitary, choose who you think is the boss of the endocrine system and provide as much evidence as you can to support your position. You may choose the hypothalamus, the posterior pituitary, anterior pituitary or a combination of these structures. You may wish to discuss your ideas with your instructor or post your position and evidence on the discussion board for your peers to evaluate. Read at least two other students’ positions and discuss their evidence.

 

Self Check

Review the lesson, then complete the following multiple choice questions which will help assess your understanding of the concepts presented in this lesson. Check your answers and discuss any questions that you do not understand with your instructor.

 

Use the following diagram to answer the next two questions.

 

Inquiry into Biology (Whitby, ON: McGraw-Hill Ryerson, 2007), 445, fig. 13. 12. Reproduced by permission.

1. The structures labeled A and F on this diagram respectively are the
   
   
   1. hypothalamus and posterior pituitary.
   2. hypothalamus and anterior pituitary.
   3. anterior pituitary and posterior pituitary.
   4. posterior pituitary and anterior pituitary

2. The function of the structure labeled C on the diagram is to
   
   
   1. synthesize antidiuretic hormone and oxytocin.
   2. stimulate release of ADH and oxytocin.
   3. stimulate production of tropic hormones
   4. regulate the levels of ADH released into the blood.

Use the following diagram to answer the next two questions.

 

3. Which endocrine gland shown on this diagram would be directly responsible for the development of dwarfism or gigantism in humans?
   
   
   1. G
   2. F
   3. B
   4. D

4. Which of the following best explains the development of acromegaly in adults?
   
   
   1. increased production of TSH
   2. increased production of ACTH
   3. increased production of ADH
   4. increased production of hGH

Use the following feedback loop and information to answer the next two questions.

 

 

For this question, assume that the feedback loop shown is for a hormone primarily responsible for regulating the metabolic rate. The target cells for this hormone are all the cells of the body which it stimulates to metabolize at a faster rate.

5. Which row correctly identifies the hormones indicated by the numbers 1. 2, and 3 on the feedback loop?

Row	Hormone #1	Hormone #2	Hormone #3
a.	Releasing hormone from hypothalamus	Thyroid stimulating hormone	Thyroxine
b.	Releasing hormone from hypothalamus	Adrenocorticotropic hormone	Cortisol
c.	Inhibiting hormone from hypothalamus	Human growth hormone	Growth factors
d.	Inhibiting hormone from hypothalamus	Pancreas stimulating hormone	Insulin

6. The number 5 on the diagram would cause the release of the following hormone:
   
   
   1. releasing hormone
   2. inhibiting hormone
   3. ACTH
   4. TSH

7. The pituitary is often called the “master gland” because it
   
   
   1. receives impulses directly from the brain
   2. controls every other gland and organ in the body
   3. secretes hormones that control the functions of exocrine glands
   4. produces hormones that regulate the activities of other endocrine glands

8. An abnormally large volume of urine may be produced after a person drinks alcoholic beverages. It is likely that ethyl alcohol affects normal secretion of
   
   
   1. antidiuretic hormone
   2. thyroxine
   3. cortisol
   4. aldosterone

Use the following information to answer the next question.

 

The following procedures and observations were used to determine the function of secretions from an animal organ suspected of being an endocrine gland.

 

The suspected endocrine gland was surgically removed from the animal.
Symptoms in the animal were observed.
A chemical mixture was extracted from the suspected endocrine gland.
The chemical mixture was injected into the animal.
Symptoms in the animal were no longer observed.

Normal female rats injected with the chemical mixture showed accelerated body growth and increased thyroxine production.

9. Based on these observations, the organ was the
   
   
   1. thyroid gland
   2. posterior pituitary
   3. hypothalamus
   4. anterior pituitary

Use the following information to answer the next question.

 

 

10. If Gland 1 is the pituitary gland, the row that identifies Hormone 1, Gland 2, and Hormone 2 is

Row	Hormone 1	Gland 2	Hormone 2
a.	ACTH	Adrenal Cortex	Adrenaline
b.	TSH	Thyroid	Thyroxine
c.	ACTH	Adrenal Medulla	Cortisol
d.	ADH	Kidney	Aldosterone

 

Use the following information to answer the next question.

 

11. Normally inhibition of the pituitary gland would occur if the secretion of Hormone X
    
    
    1. increased, causing a decrease in the secretion of Hormone Y
    2. decreased, causing a decrease in the secretion of Hormone Y
    3. increased, causing an increase in the secretion of Hormone Y
    4. decreased, causing an increase in the secretion of Hormone Y

 

Reflect on the Big Picture

The endocrine system is self-regulating through its boss and through negative feedback mechanisms. What happens when the CEO or boss of the endocrine system is not doing its job, as in Emily’s case? How are the regulatory pathways affected when tropic hormones are AWOL [absent with-out leave]? In Lesson 3 you will examine Emily’s inability to regulate the stress hormones produced by the adrenal gland because her pituitary tumor causes too much ACTH to be secreted. In Lesson 4 you will examine the effects of her body not being able to regulate the thyroid hormone thyroxine because the tumor causes the under secretion of TSH.