Lesson 7 — Synaptic and Neuromuscular Transmission


Self-Check


    Avoiding a Collision

    You are driving down a highway at night when a deer jumps in front of your vehicle. You slam on the brakes and avoid a collision.


  1. Which row below best describes the initial reaction of your autonomic nervous system to this situation? 

  2. Row System Involved Neurotransmitter Response
    a. Sympathetic Nervous System Norepinephrine Heart rate increases; pupils of eyes dilate.
    b. Parasympathetic Nervous System Acetylcholine Heart rate increases; pupils of eyes dilate.
    c. Sympathetic Nervous System Acetylcholine Heart rate increases; pupils of eyes constrict.
    d. Parasympathetic Nervous System Norepinephrine Heart rate decreases; pupils of eyes constrict.


  3. Which row below describes the reaction of your autonomic nervous system several minutes after the incident.

  4. Row System Involved Neurotransmitter Response
    a. Sympathetic Nervous System Norepinephrine Heart rate increases; pupils of eyes dilate.
    b. Parasympathetic Nervous System Norepinephrine Heart rate increases; pupils of eyes dilate.
    c. Sympathetic Nervous System Acetylcholine Heart rate decreases; pupils of eyes constrict.
    d. Parasympathetic Nervous System Acetylcholine Heart rate decreases; pupils of eyes constrict.


    Use the following information to answer the next question.


  5. Destruction of the synaptic vesicles of Neuron 1 will

    1. block the nerve impulse at W
    2. cause X to be constantly stimulated
    3. prevent depolarizations from occurring at Y
    4. result in the action of cholinesterase in Neuron 2


  6. Use the following information to answer the next question.



  7. If the structures labelled Q were absent, what effect on neural transmission would be expected?

    1. The axon would not release acetylcholine.
    2. The axon would not become depolarized.
    3. The speed of transmission would be reduced.
    4. No action potential would arrive to release neurotransmitter.


  8. Use the following information to answer the next question.

    The disease myasthenia gravis causes a person to experience muscular weakness because of the failure of neuromuscular junctions to transmit signals from nerve fibres to muscle fibres. The weakness is due to a reduced sensitivity to acetylcholine, which is necessary to stimulate the muscle fibre. People suffering from this disease often are treated with neostigmine, an anticholinesterase drug that can result in some normal muscular activity within minutes. (Guyton and Hall, 1996)

  9. Neostigmine is effective in treating this disease because it

    1. binds with cholinesterase to form acetylcholine

    2. binds with cholinesterase to increase acetylcholine production

    3. reduces the amount of active cholinesterase, thereby increasing the amount of acetylcholine available to stimulate muscle contraction

    4. increases the amount of active cholinesterase, thereby increasing the amount of acetylcholine available to stimulate muscle contraction


  10. Use the following information to answer the next question.

    Observations about a Synapse and Synaptic Transmission
    1. Only axon terminals release neurotransmitters.

    2. A neurotransmitter diffuses from an axon terminal across the synapse to the dendrites or cell body.

    3. Many transmissions across a synapse in a short time may cause fatigue of synaptic transmission.

    4. Electron micrographs of a synapse show no direct connection between the axon terminal of a presynaptic neuron and the dendrites or cell body of a postsynaptic neuron.


  11. The assumption that axon terminals contain a limited amount of neurotransmitter could account for observation 

    1. 1
    2. 2
    3. 3
    4. 4


  12. Use the following information to answer the next question.

    Alternative medicine, such as aromatherapy, is becoming increasingly popular in western society. Aromatherapy uses natural oils and plant extracts. The scents of the oils and extracts are inhaled or the fragrant oils are massaged into the skin. Proponents of aromatherapy hypothesize that odours affect the brain and its release of neurochemicals to relieve pain.

    Hypothesized Steps in Aromatherapy Action

    1. Olfactory neurons depolarize.
    2. Olfactory receptors are stimulated.
    3. Neurochemicals affect pain interpretation.
    4. Neurochemicals are released from axon terminals.

    Numerical Response


  13. If the hypothesis is correct, the order in which the steps would occur to result in pain relief in a person having just inhaled the scent from an aromatherapy oil or extract is ______, ______, ______, and ______.


  14. While working in a lab, you accidentally mixed some unknown chemicals and a vapour was produced that diffused throughout the lab.  Soon, the lab animals in the room collapsed, unable to move. You made a quick examination of the animals and found their musculature to be very loose and relaxed. You concluded that the vapour became internalized in the animals by way of the lungs to the blood, which distributed the vapour throughout the animals' bodies. The symptoms shown by the lab animals may lead you to conclude that the vapour could have 

    1. stimulated the action of the enzyme cholinesterase
    2. inhibited the production of acetylcholine by the axon endings of neurons
    3. inhibited the formation of synaptic transmission chemical produced by the dendrites
    4. stimulated the axon endings to secrete large amounts of acetylcholine

Self-Check Answers


  1. a
  2. d
  3. c
  4. c
  5. c
  6. c
  7. 2, 1, 4, 3
  8. b

Biology 30 © 2008  Alberta Education & its Collaborative Partners ~ Updated by ADLC 2019