Module 2 Lesson 1 - 2
Read pages 436 - 442
In the previous module, you learned about the basic unit of the nervous system, the neuron, and how communication occurs through neural pathways. Now, you will learn about the major glands of the endocrine system and how communication occurs through special chemical messengers called hormones.
Endocrine glands are ductless glands. They do not release their secretions into ducts as exocrine glands do. Instead, endocrine glands secrete their hormones directly into the blood, which acts as their transport medium. As the hormones travel in the blood and encounter cells, only those cells with special receptors react to their presence. These cells are called target cells.
As a result, hormones usually are slower to prompt responses and, typically, are less specific than the nervous system is.
Lipid-soluble hormones and water-soluble hormones activate their target cells very differently. Lipid-soluble hormones diffuse through the lipid bilayer and attach to receptor proteins inside the cell, resulting in changes to the cell. Water-soluble hormones attach to the receptor proteins located on the surface of the cells, resulting in a cascade of reactions.
Hormones interact, and in many instances, one hormone counteracts the action of a second hormone. Hormones such as these are called antagonistic hormones.



Endocrine Glands, Their Hormones, Target Cells, and Main Functions (Exclude 5 and 10)
Endocrine Gland | Hormone | Target Cells | Primary Functions | |
1 | Hypothalamus | Releasing / Inhibiting Hormones | Pituitary Gland | Regulates secretion by anterior pituitary |
2a | Anterior Pituitary | Thyroid Stimulating Hormone (TSH) | Thyroid Gland | Stimulates thyroid gland to secrete thyroxine |
Adrenocorticotropic Hormone (ACTH) |
Adrenal Cortex |
Stimulates adrenal cortex to secrete cortisol | ||
Growth Hormone (hGH) | Most Cells | Stimulates cell division, growth of bones, and metabolism | ||
Follicle Stimulating Hormone (FSH)
Unit B |
Ovaries / Testes | Stimulates production of egg and sperm cells | ||
Luteinizing Hormone (LH)
Unit B |
Ovaries / Testes | Stimulates production of male and female sex hormones | ||
Prolactin
Unit B |
Mammary Glands | Stimulates milk production | ||
2b | Posterior Pituitary | Antidiuretic Hormone (ADH) | Kidneys |
Increases water reabsorption |
Oxytocin
Unit B |
Smooth Muscle Cells of Uterus / Breasts | Stimulates contraction of uterus and release of milk by breast glands | ||
3 | Parathyroid Glands | Parathyroid hormone (PTH) | Bone cells | Stimulates calcium release from bones |
4
|
Thyroid Gland | Thyroxine | Most cells | Increases metabolic rate and regulates growth and development |
Calcitonin | Bone cells | Stimulates bones to absorb calcium | ||
6 | Adrenal Medulla | Epinephrine / Norepinephrine | Most Cells | Fight or flight hormones |
6 | Adrenal Cortex |
Cortisol |
Most cells |
Raises blood glucose and breaks down protein |
|
Aldosterone |
Kidney |
Increases sodium retention and increases water reabsorption |
|
7
|
Pancreas |
Insulin |
Most cells |
Increases permeability of glucose in cells; stimulates liver cells to convert glucose to glycogen |
Glucagon | Liver cells | Stimulates release of glucose by converting glycogen to glucose | ||
8 | Ovaries |
Estrogen
Unit B |
Uterus / Other cells |
Stimulates growth of uterine lining; stimulates development of female secondary sex characteristics
|
Progesterone
Unit B |
Uterus | Promotes growth of uterine lining; inhibits uterine contractions during pregnancy | ||
9 | Testes |
Testosterone
Unit B |
Testes / Other cells |
Promotes sperm production; stimulates development of male secondary sex characteristics
|
Inhibin
Unit B |
Testes | Inhibits sperm production |
Watch and Listen
To explore further and review these concepts visually, watch the following segments of Biologix-9.
Self-Check
This interactive drag and drop exercise in two parts is based on a typical diagram of the glands of the endocrine system. On the diagram, the glands are numbered.
-
In the first part of the exercise, match by dragging the name of the gland to the correct numbered structure.
- In the second part of the interactive exercise, match by dragging the name of the hormone to the gland that produces it. Remember that some glands produce more than one hormone.