3.5 Energy for Muscle Contraction
Unit D
Module 9 ~ Lesson 3
Energy for Muscle Contraction

Muscle contraction requires a continuous supply of energy in the form of ATP. There are three main sources of ATP.
-
creatine phosphate (sometimes referred to as the phosphagen system )
- aerobic respiration of glucose
- fermentation of glucose (also known as anaerobic respiration and/or as the lactic acid system )
During prolonged endurance exercise, such as running a marathon, a depletion of muscle sugar stores, a decrease in blood glucose, dehydration, or an increase in body temperature contribute to fatigue. During an intense muscular activity, lactic acid is formed through glycolysis and lactic acid fermentation.
The H+ ions from lactic acid decrease the pH of the muscle; this may inhibit metabolic processes and, thereby, decrease work output.

Energy Source |
Aerobic or Anaerobic |
Site of Reaction |
Initial Reactant Required for Contraction |
Final Products of Reaction |
Relative Amounts of ATP Produced |
Creatine Phosphate | anaerobic doesn't require oxygen | within the muscle myofilaments | creatine phosphate | creatine + ATP | high, for a short period of time |
Aerobic Cellular Respiration | aerobic requires oxygen | mitochondria of muscle cells | glucose or fatty acids | CO 2 + H 2 O + ATP | high |
Fermentation | anaerobic, doesn't require oxygen | the cytoplasm of muscle cells | glucose or fatty acids | lactate (lactic acid) + ATP | low |