1. Module 8

1.4. Page 2

Lesson 1

Module 8—Populations, Individuals, and Gene Pools

 

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Field mouse eating berries

© Eduard Kyslynskyy/shutterstock

 

Describing Gene Pools

 

When people are interested in the genetic composition of a population, they are interested in its gene pool. Consider a population of only ten field mice on the southern Alberta prairies. Assume that mice have two different alleles for coat colour, brown (B) and white (b). The genotypes for the mice are shown in the diagram below.

 


Imagine that each mouse can throw its two alleles for coat colour into a basket—this is the gene pool of the population.

 

The gene pool can be described in three ways:

  • by its genotype frequencies
  • by its phenotype frequencies
  • by its allele frequencies

Frequency is measured by dividing the number of a particular subgroup by the total group. The symbol f indicates frequency. The following examples show how to calculate genotype, phenotype, and allele frequency in the population for these field mice.

 

Genotype Frequency: How common is each genotype in the population?

 


 

Note: The shorthand f(BB) will be used to replace the long-hand "frequency of the BB genotype.”

 

 

Phenotype Frequency: How common is each phenotype in the population?

 


 

Note: The shorthand f(Black) will be used to replace the long-hand “frequency of the brown phenotype.”

 

 

Allele Frequency: How common is each allele in the population?

 


 

Note: The shorthand f(B) will be used to replace the long-hand “frequency of the B allele.” Remember that there are ten individuals, so there are 20 alleles in total.

 

 

For population geneticists, the most useful way to describe a gene pool is by its allele frequencies. Do you know why?

 

Self-Check 

 

SC 1. In a population of ten mice, suppose three have the homozygous dominant genotoype, two are heterozygotes, and five have the homozygous recessive genotoype. What is the frequency of each genotype in the population? What is the frequency of the dominant and recessive alleles?

 

Check your work.
Self-Check Answers
 

SC 1.

 

Genotype Frequencies

 

3/10 mice are AA, so f(AA) = 0.3.
2/10 mice are Aa, so f(Aa) = 0.2.
5/10 mice are aa, so f(aa) = 0.5.

 

Allele Frequencies

 

(Reminder: Ten mice have two alleles each, so there are a total of 20 alleles in the gene pool.)

 

3 mice are AA, so they have 6 A alleles.

2 mice are Aa, so they have 2 A alleles and 2 a alleles.

5 mice are aa, so they have 10 a alleles.